Chem 2402K
Nuclear Magnetic Resonance Spectroscopy
Leaning Objectives:
After study, the student will
1. know the reaction of alcohols including:
a. Oxidation of alcohols using chromic acid, pcc and biological oxidation in liver.
B. Reduction of alcohols
C. Reactions of alcohols with HBr
D. Reaction of alcohols with HCl
E. Reactions of alcohols with phosphorus halides
F. Dehydration reactions of alcohols
G. Esterification of alcohols
H. Periodic acid cleavage of diols
2. Formation and reactions of alkoxides
3. differentiate between primary,
secondary and tertiary alcohols.
4. name alcohols using common and
IUPAC names.
5. know the physical properties of
alcohols.
6. know the reactions used in preparation of alcohols including
oxymercuration-demercuration, hydroboration-oxidation,
hydrolysis of alkyl halides, addition of potassium permanganate, use of lithium
aluminum hydride and sodium borohydride, and Grignard
reagent.
7. Know that ketones and aldehydes can be converted to alcohols using Raney nickle catalyst.
8. Know what are phenols and give
example
9. Know what are thiols,
how to name them and where they are used
10. Know how to prepare thiols.
11. Know the commercial preparation and uses of ethanol,
methanol and isopropyl alcohol
Learning Activity:
1. Read chapter 13 in Organic Chemistry : A Biological Approach by McMurry
2. Do the following problems: 24, 29, 34, 36, 38